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FOX04 10mg
(FOXO4‑DRI)

(Tetratetracontapeptide–46 Amino Acids)

( Product no. 871-13 )

£78.99

FOXO4‑DRI Sequence for Mechanistic Research

FOXO4 Peptide is a regulatory peptide compound researched for its role in cellular senescence signalling, transcription factor modulation, and cell cycle regulation within controlled laboratory environments. It is studied for its interaction with FOXO4 related pathways involved in stress response, DNA damage signalling, and apoptosis regulation. Supplied in lyophilised form, this research grade peptide supports in vitro studies focused on cellular ageing mechanisms, gene expression control.

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FOXO4 Peptide 10mg

Premium Grade | UK Supply

Product Overview

FOXO4 Peptide is a sequence specific peptide compound developed for research into forkhead box O transcription factor signalling pathways. It is designed to interact with molecular processes associated with FOXO4 mediated regulation of cell survival, oxidative stress response, and cellular homeostasis. The peptide is produced using controlled laboratory processes to ensure sequence fidelity, purity, and batch reproducibility. Its molecular composition allows targeted interaction with intracellular regulatory complexes involved in transcriptional control. Supplied in lyophilised format, the compound demonstrates favourable stability characteristics under appropriate laboratory storage conditions, supporting extended research programmes focused on senescence modulation, transcription factor activity, and peptide driven regulation of cell fate decisions.

 

Scientific Background

Scientific research into FOXO4 Peptide centres on its relevance to cellular senescence and stress response pathways governed by FOXO family transcription factors. FOXO4 plays a key role in regulating gene expression linked to cell cycle arrest, DNA repair processes, and resistance to oxidative stress. Peptide based modulation of these pathways allows researchers to study senescent cell persistence, apoptosis resistance mechanisms, and transcriptional control dynamics. Investigations explore interactions with p53 signalling, nuclear localisation behaviour, and downstream gene regulatory networks. The predictable activity profile of the peptide enables controlled examination of cellular ageing processes, signalling thresholds, and regulatory feedback mechanisms within in vitro experimental systems.

 

Research Applications

In laboratory research environments, FOXO4 Peptide is utilised in in vitro models examining cellular senescence, transcription factor regulation, and stress response signalling. It is applied in studies investigating senescent cell survival mechanisms, apoptosis sensitivity, and gene expression modulation. Additional applications include cellular ageing research, oxidative stress assays, and peptide based exploration of transcriptional control networks. The compound is also employed in comparative studies assessing regulatory peptide influence on senescence pathways and cell fate determination. Its reproducible activity supports use as a reference compound in ageing research.

 

Technical Specification

  • Contents: 10mg FOX04
  • Form: Lyophilized powder
  • Purity: >99% (HPLC Verified)
  • Storage: Store between 2°C and 8°C
  • Molecular Formula: C₂₂₈ H₃₈₈ N₈₆ O₆₄
  • Sequence: D-(Leu-Thr-Leu-Arg-Lys-Glu-Pro-Glu-Glu-Tyr-Leu-Leu-Gln-Asn-Gln-Arg-Arg-Arge
  • Peptide Length: 18 Amino-Acids 
  • pH Range: 5.6-7.2
  • Storage: Store between 2°C and 8°C

Note: Reconstitute with Bacteriostatic (BAC) water for best results.

 

Related Research Compounds

SS-31 10mg
KVP 10mg
Epitalon 10mg

 

Internal Research Sources

Trade supply
Peptides sets
Bulk purchase range

 

Disclaimer

For research purpose only, Not for human consumption.

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How to Reconstitute Your Peptides

 

What You Will Need 

  • Lyophilized peptide vial
  • Sterile solvent (such as bacteriostatic water or another suitable choice)
  • 1 ml sterile syringe with a fine (29–30g) needle
  • Sterile alcohol wipes
  • Calculator for dilution and dosage accuracy
  • Labels for marking each aliquot with concentration and date
  • Sterile workspace or biosafety cabinet (recommended for best practice)

 

Preparation Steps

Allow the vial to reach room temperature

This helps prevent condensation, which can compromise sterility when you open the vial.

Draw up the solvent

Using a sterile syringe, measure the precise amount of bacteriostatic water or your chosen solvent.

Inject the solvent gently

Insert the needle into the vial at a 45-degree angle so the liquid runs down the inside wall, which reduces bubbling and foam.

Dissolve the peptide

Swirl the vial gently until the peptide powder is completely dissolved. Avoid shaking, as this can damage the peptide bonds.

Aliquot the solution

If smaller, single-use portions are needed, divide the solution into sterile microtubes using a new, sterile syringe or pipette for each.


 

Learn More

 

 

Tips for Storing Your Peptides

 


General Storage Guidelines

  • Store all peptides in airtight, moisture-resistant containers to prevent exposure to humidity.
  • Minimise freeze-thaw cycles by dividing peptides into single-use aliquots whenever possible.
  • Protect peptides from light, especially if they are modified or known to be photosensitive, by storing them in amber vials or wrapping them in foil.
  • Always practice sterile handling and accurate labelling, including peptide name, concentration, date, and storage conditions.

Lyophilised Peptides

  • Keep lyophilised (freeze-dried) peptides at minus 20°C or lower for long-term stability.
  • Ensure the container is sealed tightly to keep out moisture.
  • Allow the vial to reach room temperature before opening to avoid condensation, which can degrade the peptide.
  • Only open vials in a dry environment to prevent humidity from affecting the product.

Reconstituted Peptides

  • Store peptides reconstituted with sterile water or buffer at 2°C to 8°C and use within 1–12 weeks.
  • If peptides are dissolved in DMSO or other organic solvents, store them at minus 20°C and protect from light.
  • Always aliquot into single-use volumes immediately after reconstitution to avoid repeated freeze-thaw cycles.
  • Clearly label all aliquots with relevant information and only thaw as needed to preserve the peptide’s activity and integrity.

Read More on Storage Guidelines

 

 

Shipping and Postage

 

UK & European Delivery

Evri UK Tracked 1-2 Business Days 

This costs; £4.99 per order

European DHL Express Tracked 1-2 Days 

This cost; £24.99 per order

Bioplex Peptides offers fast and reliable 1-2 days delivery across the UK with full tracking included. Note; Due to the nature of our products, we only dispatch samples between Monday-Thursday, orders after 12pm will be shipped the following day. 

*We aim to dispatch and deliver orders within the stated timeframes, but delays can occur due to severe weather, transport issues, public holidays, or other unforeseen events. Once an order has been dispatched, extended delivery times are outside our control.

Tax & Duty Information

Shipping Policy

International Delivery

United States of America & Canada 1-2 Business Days

This cost; £24.99 per order
 

International Delivery 1-3 Business Days

This cost; £29.99 per order

Bioplex Peptides offers fast and reliable 1-3 days worldwide delivery with full tracking included using the worlds fastest and most reliable courier available with a discounted rate for all EU & International customers. Delays may occur due to natural causes such as severe weather conditions, transportation disruptions, public holidays, or other unforeseen events. All international samples ship Monday–Saturday, ensuring steady worldwide delivery scheduling.

Tax & Duty Information

Shipping Policy

Order Processing

Orders are typically processed within 24hrs after payment confirmation. Custom peptide synthesis orders and wholesale orders may require additional lead time depending on complexity and quantity. Clients will be notified of estimated delivery timelines upon order confirmation.

Shipping Methods and Carriers

We utilize reliable courier services such DHL Express Premium 1-2 Business days for all International deliveries and Evri & Royal Mail tracked 1-2 days delivery for all United Kingdom deliveries to ensure timely and traceable delivery. Shipping options may vary depending on destination, order size, and regulatory requirements.

BioPleX Peptides is not responsible for delays caused by customs clearance, weather disruptions, or carrier-related issues.

Returns and Refunds

Due to the specialised and perishable nature of our research peptide products, BioPlex Peptides does not offer general refunds or accept returns once an order has been shipped. All purchases are considered final unless they meet specific criteria outlined below.

Refunds and Replacements

We do not provide refunds for products that have been correctly fulfilled and delivered. However, if an item arrives damaged, compromised, or incorrect due to an error on our part, we will offer a replacement at no additional cost. Claims must be submitted within 48 hours of delivery, accompanied by photographic evidence and a description of the issue.

Missing Parcels

If your parcel has not arrived within the estimated delivery window, please contact our logistics team promptly. We will initiate an investigation with the carrier and provide updates throughout the process. If the parcel is confirmed lost, we will issue a replacement shipment or credit, depending on the circumstances.

Order Cancellation

Orders may be cancelled within 24 hours of placement, provided production has not yet begun. Custom peptide synthesis orders are non-cancellable once processing has started. To request a cancellation, please email us at enquiries@bioplexpeptides.co.uk with your order number and reason for cancellation.

Damaged or Incorrect Items

In the rare event that you receive a damaged or incorrect item, please notify us within 48 hours of receipt. Include your order number, photos of the product and packaging, and a description of the issue. We will assess the claim and, if validated, arrange for a replacement to be shipped promptly.

 

Read More on Our Returns & Refunds Policy

 

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