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AICAR 50mg
(Acadesine)

(Small Molecule Nucleotide Analogue)

( Product no. 871-90 )

£28.99

AICAR is a Metabolic Research Compound Linked to AMPK Pathways

AICAR is a laboratory research compound widely referenced in studies of cellular energy sensing and metabolic pathway regulation. In controlled scientific settings, it is commonly examined for its interaction with AMPK related signalling and downstream biochemical processes linked to energy balance. Researchers use AICAR in analytical and experimental models exploring metabolism, substrate handling, and cellular response behaviour.

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AICAR 50mg
(Acadesine)

Premium Grade | UK Supply

Product Overview

AICAR (5 aminoimidazole 4 carboxamide ribonucleotide) is a small molecule research compound widely used in laboratory studies focused on cellular energy sensing and metabolic signalling. It is not a peptide, but it is often listed alongside peptide research materials because it is frequently used within adjacent biochemical and cell signalling workflows. AICAR is typically supplied as a defined reference compound produced under controlled manufacturing and purification conditions to support identity confirmation and reproducible handling in experimental settings. In vitro, AICAR is examined for its ability to enter cells and be converted to the ribonucleotide form (commonly referred to as ZMP), supporting controlled interrogation of AMPK linked pathway behaviour and related downstream signalling networks. Supplied in a stable format, it supports accurate solution preparation and concentration control for research assays.
 

Scientific Background

From a molecular science perspective, AICAR is studied primarily as a precursor that can be phosphorylated intracellularly to form ZMP, an AMP mimetic that is frequently examined in research models of energy stress signalling. This biochemical conversion is central to why AICAR is used in signalling research, as ZMP is investigated for its capacity to influence AMPK associated pathway activation and downstream regulatory nodes involved in metabolic adaptation logic. Research literature explores how AICAR derived ZMP impacts kinase cascade coordination, transcriptional regulation programmes, and substrate utilisation modelling within controlled experimental systems. AICAR is also used to study cross talk between AMPK linked signalling and other regulatory pathways, including mTOR related nodes, autophagy marker pathways, and mitochondrial biogenesis related signalling readouts, depending on the model and assay configuration.

 

Research Applications

AICAR is extensively researched in in vitro studies examining AMPK related signalling activation, metabolic pathway modelling, and cellular energy regulation mechanisms. Researchers use AICAR in controlled cell based systems to investigate pathway timing, dose response behaviour, and downstream marker responses such as phosphorylation panels, gene expression signatures, and metabolic flux readouts. It is also used in method development workflows where reproducible pathway activation is needed to validate assay sensitivity, optimise detection windows, and compare signalling responses across cell types or engineered lines. In analytical contexts, AICAR supports LC MS quantification methods, stability profiling, and identity confirmation as part of compound handling and experimental validation. 

 

Technical Specifications

  • Contents: 50mg AICAR
  • Form: Lyophilised Powder
  • Purity: >99% (HPLC Verified)
  • Molecular Formula: C₉H₁₄N₄O₅
  • Sequence: N/A (AICAR is not a peptide)
  • Peptide Length: N/A
  • pH Range: 4.9–6.5
  • Storage: Store Between 1°C and 5°C

Note: Reconstitute with 50% Bacteriostatic (BAC) water  for best results.

 

Related Research Compounds

Retatrutide 20mg
MOT-c 10mg
Cagrilintide 10mg

 

Internal Research Sources

Trade supply
Peptides sets
Bulk purchase range

 

Disclaimer

For research purposes only, Not for human consumption. 

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How to Reconstitute Your Peptides

 

What You Will Need 

  • Lyophilized peptide vial
  • Sterile solvent (such as bacteriostatic water or another suitable choice)
  • 1 ml sterile syringe with a fine (29–30g) needle
  • Sterile alcohol wipes
  • Calculator for dilution and dosage accuracy
  • Labels for marking each aliquot with concentration and date
  • Sterile workspace or biosafety cabinet (recommended for best practice)

 

Preparation Steps

Allow the vial to reach room temperature

This helps prevent condensation, which can compromise sterility when you open the vial.

Draw up the solvent

Using a sterile syringe, measure the precise amount of bacteriostatic water or your chosen solvent.

Inject the solvent gently

Insert the needle into the vial at a 45-degree angle so the liquid runs down the inside wall, which reduces bubbling and foam.

Dissolve the peptide

Swirl the vial gently until the peptide powder is completely dissolved. Avoid shaking, as this can damage the peptide bonds.

Aliquot the solution

If smaller, single-use portions are needed, divide the solution into sterile microtubes using a new, sterile syringe or pipette for each.


 

Learn More

 

 

Tips for Storing Your Peptides

 


General Storage Guidelines

  • Store all peptides in airtight, moisture-resistant containers to prevent exposure to humidity.
  • Minimise freeze-thaw cycles by dividing peptides into single-use aliquots whenever possible.
  • Protect peptides from light, especially if they are modified or known to be photosensitive, by storing them in amber vials or wrapping them in foil.
  • Always practice sterile handling and accurate labelling, including peptide name, concentration, date, and storage conditions.

Lyophilised Peptides

  • Keep lyophilised (freeze-dried) peptides at minus 20°C or lower for long-term stability.
  • Ensure the container is sealed tightly to keep out moisture.
  • Allow the vial to reach room temperature before opening to avoid condensation, which can degrade the peptide.
  • Only open vials in a dry environment to prevent humidity from affecting the product.

Reconstituted Peptides

  • Store peptides reconstituted with sterile water or buffer at 2°C to 8°C and use within 1–12 weeks.
  • If peptides are dissolved in DMSO or other organic solvents, store them at minus 20°C and protect from light.
  • Always aliquot into single-use volumes immediately after reconstitution to avoid repeated freeze-thaw cycles.
  • Clearly label all aliquots with relevant information and only thaw as needed to preserve the peptide’s activity and integrity.

Read More on Storage Guidelines

 

 

Shipping and Postage

 

UK & European Delivery

Evri UK Tracked 1-2 Business Days 

This costs; £4.99 per order

European DHL Express Tracked 1-2 Days 

This cost; £24.99 per order

Bioplex Peptides offers fast and reliable 1-2 days delivery across the UK with full tracking included. Note; Due to the nature of our products, we only dispatch samples between Monday-Thursday, orders after 12pm will be shipped the following day. 

*We aim to dispatch and deliver orders within the stated timeframes, but delays can occur due to severe weather, transport issues, public holidays, or other unforeseen events. Once an order has been dispatched, extended delivery times are outside our control.

Tax & Duty Information

Shipping Policy

International Delivery

United States of America & Canada 1-2 Business Days

This cost; £24.99 per order
 

International Delivery 1-3 Business Days

This cost; £29.99 per order

Bioplex Peptides offers fast and reliable 1-3 days worldwide delivery with full tracking included using the worlds fastest and most reliable courier available with a discounted rate for all EU & International customers. Delays may occur due to natural causes such as severe weather conditions, transportation disruptions, public holidays, or other unforeseen events. All international samples ship Monday–Saturday, ensuring steady worldwide delivery scheduling.

Tax & Duty Information

Shipping Policy

Order Processing

Orders are typically processed within 24hrs after payment confirmation. Custom peptide synthesis orders and wholesale orders may require additional lead time depending on complexity and quantity. Clients will be notified of estimated delivery timelines upon order confirmation.

Shipping Methods and Carriers

We utilize reliable courier services such DHL Express Premium 1-2 Business days for all International deliveries and Evri & Royal Mail tracked 1-2 days delivery for all United Kingdom deliveries to ensure timely and traceable delivery. Shipping options may vary depending on destination, order size, and regulatory requirements.

BioPleX Peptides is not responsible for delays caused by customs clearance, weather disruptions, or carrier-related issues.

Returns and Refunds

Due to the specialised and perishable nature of our research peptide products, BioPlex Peptides does not offer general refunds or accept returns once an order has been shipped. All purchases are considered final unless they meet specific criteria outlined below.

Refunds and Replacements

We do not provide refunds for products that have been correctly fulfilled and delivered. However, if an item arrives damaged, compromised, or incorrect due to an error on our part, we will offer a replacement at no additional cost. Claims must be submitted within 48 hours of delivery, accompanied by photographic evidence and a description of the issue.

Missing Parcels

If your parcel has not arrived within the estimated delivery window, please contact our logistics team promptly. We will initiate an investigation with the carrier and provide updates throughout the process. If the parcel is confirmed lost, we will issue a replacement shipment or credit, depending on the circumstances.

Order Cancellation

Orders may be cancelled within 24 hours of placement, provided production has not yet begun. Custom peptide synthesis orders are non-cancellable once processing has started. To request a cancellation, please email us at enquiries@bioplexpeptides.co.uk with your order number and reason for cancellation.

Damaged or Incorrect Items

In the rare event that you receive a damaged or incorrect item, please notify us within 48 hours of receipt. Include your order number, photos of the product and packaging, and a description of the issue. We will assess the claim and, if validated, arrange for a replacement to be shipped promptly.

 

Read More on Our Returns & Refunds Policy

 

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