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AICAR is a laboratory research compound widely referenced in studies of cellular energy sensing and metabolic pathway regulation. In controlled scientific settings, it is commonly examined for its interaction with AMPK related signalling and downstream biochemical processes linked to energy balance. Researchers use AICAR in analytical and experimental models exploring metabolism, substrate handling, and cellular response behaviour.
AICAR (5 aminoimidazole 4 carboxamide ribonucleotide) is a small molecule research compound widely used in laboratory studies focused on cellular energy sensing and metabolic signalling. It is not a peptide, but it is often listed alongside peptide research materials because it is frequently used within adjacent biochemical and cell signalling workflows. AICAR is typically supplied as a defined reference compound produced under controlled manufacturing and purification conditions to support identity confirmation and reproducible handling in experimental settings. In vitro, AICAR is examined for its ability to enter cells and be converted to the ribonucleotide form (commonly referred to as ZMP), supporting controlled interrogation of AMPK linked pathway behaviour and related downstream signalling networks. Supplied in a stable format, it supports accurate solution preparation and concentration control for research assays.
From a molecular science perspective, AICAR is studied primarily as a precursor that can be phosphorylated intracellularly to form ZMP, an AMP mimetic that is frequently examined in research models of energy stress signalling. This biochemical conversion is central to why AICAR is used in signalling research, as ZMP is investigated for its capacity to influence AMPK associated pathway activation and downstream regulatory nodes involved in metabolic adaptation logic. Research literature explores how AICAR derived ZMP impacts kinase cascade coordination, transcriptional regulation programmes, and substrate utilisation modelling within controlled experimental systems. AICAR is also used to study cross talk between AMPK linked signalling and other regulatory pathways, including mTOR related nodes, autophagy marker pathways, and mitochondrial biogenesis related signalling readouts, depending on the model and assay configuration.
AICAR is extensively researched in in vitro studies examining AMPK related signalling activation, metabolic pathway modelling, and cellular energy regulation mechanisms. Researchers use AICAR in controlled cell based systems to investigate pathway timing, dose response behaviour, and downstream marker responses such as phosphorylation panels, gene expression signatures, and metabolic flux readouts. It is also used in method development workflows where reproducible pathway activation is needed to validate assay sensitivity, optimise detection windows, and compare signalling responses across cell types or engineered lines. In analytical contexts, AICAR supports LC MS quantification methods, stability profiling, and identity confirmation as part of compound handling and experimental validation.
Note: Reconstitute with 50% Bacteriostatic (BAC) water for best results.
Retatrutide 20mg
MOT-c 10mg
Cagrilintide 10mg
Trade supply
Peptides sets
Bulk purchase range
AICAR is a laboratory research compound widely referenced in studies of cellular energy sensing and metabolic pathway regulation. In controlled scientific settings, it is commonly examined for its interaction with AMPK related signalling and downstream biochemical processes linked to energy balance. Researchers use AICAR in analytical and experimental models exploring metabolism, substrate handling, and cellular response behaviour.
AICAR (5 aminoimidazole 4 carboxamide ribonucleotide) is a small molecule research compound widely used in laboratory studies focused on cellular energy sensing and metabolic signalling. It is not a peptide, but it is often listed alongside peptide research materials because it is frequently used within adjacent biochemical and cell signalling workflows. AICAR is typically supplied as a defined reference compound produced under controlled manufacturing and purification conditions to support identity confirmation and reproducible handling in experimental settings. In vitro, AICAR is examined for its ability to enter cells and be converted to the ribonucleotide form (commonly referred to as ZMP), supporting controlled interrogation of AMPK linked pathway behaviour and related downstream signalling networks. Supplied in a stable format, it supports accurate solution preparation and concentration control for research assays.
From a molecular science perspective, AICAR is studied primarily as a precursor that can be phosphorylated intracellularly to form ZMP, an AMP mimetic that is frequently examined in research models of energy stress signalling. This biochemical conversion is central to why AICAR is used in signalling research, as ZMP is investigated for its capacity to influence AMPK associated pathway activation and downstream regulatory nodes involved in metabolic adaptation logic. Research literature explores how AICAR derived ZMP impacts kinase cascade coordination, transcriptional regulation programmes, and substrate utilisation modelling within controlled experimental systems. AICAR is also used to study cross talk between AMPK linked signalling and other regulatory pathways, including mTOR related nodes, autophagy marker pathways, and mitochondrial biogenesis related signalling readouts, depending on the model and assay configuration.
AICAR is extensively researched in in vitro studies examining AMPK related signalling activation, metabolic pathway modelling, and cellular energy regulation mechanisms. Researchers use AICAR in controlled cell based systems to investigate pathway timing, dose response behaviour, and downstream marker responses such as phosphorylation panels, gene expression signatures, and metabolic flux readouts. It is also used in method development workflows where reproducible pathway activation is needed to validate assay sensitivity, optimise detection windows, and compare signalling responses across cell types or engineered lines. In analytical contexts, AICAR supports LC MS quantification methods, stability profiling, and identity confirmation as part of compound handling and experimental validation.
Note: Reconstitute with 50% Bacteriostatic (BAC) water for best results.
Retatrutide 20mg
MOT-c 10mg
Cagrilintide 10mg
Trade supply
Peptides sets
Bulk purchase range


Allow the vial to reach room temperature
This helps prevent condensation, which can compromise sterility when you open the vial.

Draw up the solvent
Using a sterile syringe, measure the precise amount of bacteriostatic water or your chosen solvent.

Inject the solvent gently
Insert the needle into the vial at a 45-degree angle so the liquid runs down the inside wall, which reduces bubbling and foam.

Dissolve the peptide
Swirl the vial gently until the peptide powder is completely dissolved. Avoid shaking, as this can damage the peptide bonds.

Aliquot the solution
If smaller, single-use portions are needed, divide the solution into sterile microtubes using a new, sterile syringe or pipette for each.

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Bioplex Peptides offers fast and reliable 1-3 days worldwide delivery with full tracking included using the worlds fastest and most reliable courier available with a discounted rate for all EU & International customers. Delays may occur due to natural causes such as severe weather conditions, transportation disruptions, public holidays, or other unforeseen events. All international samples ship Monday–Saturday, ensuring steady worldwide delivery scheduling.
Orders are typically processed within 24hrs after payment confirmation. Custom peptide synthesis orders and wholesale orders may require additional lead time depending on complexity and quantity. Clients will be notified of estimated delivery timelines upon order confirmation.
We utilize reliable courier services such DHL Express Premium 1-2 Business days for all International deliveries and Evri & Royal Mail tracked 1-2 days delivery for all United Kingdom deliveries to ensure timely and traceable delivery. Shipping options may vary depending on destination, order size, and regulatory requirements.
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Due to the specialised and perishable nature of our research peptide products, BioPlex Peptides does not offer general refunds or accept returns once an order has been shipped. All purchases are considered final unless they meet specific criteria outlined below.
We do not provide refunds for products that have been correctly fulfilled and delivered. However, if an item arrives damaged, compromised, or incorrect due to an error on our part, we will offer a replacement at no additional cost. Claims must be submitted within 48 hours of delivery, accompanied by photographic evidence and a description of the issue.
If your parcel has not arrived within the estimated delivery window, please contact our logistics team promptly. We will initiate an investigation with the carrier and provide updates throughout the process. If the parcel is confirmed lost, we will issue a replacement shipment or credit, depending on the circumstances.
Orders may be cancelled within 24 hours of placement, provided production has not yet begun. Custom peptide synthesis orders are non-cancellable once processing has started. To request a cancellation, please email us at enquiries@bioplexpeptides.co.uk with your order number and reason for cancellation.
In the rare event that you receive a damaged or incorrect item, please notify us within 48 hours of receipt. Include your order number, photos of the product and packaging, and a description of the issue. We will assess the claim and, if validated, arrange for a replacement to be shipped promptly.
Read More on Our Returns & Refunds Policy

If you have any questions regarding our research peptides for sale, please feel free to reach out below.